Basic Information
VIS ID
TVIS10017280
Fusion event
HBV-chr8 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1795
End
1888
Integrated sequence
TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr8
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
84907675/83995440 (Hg38)
End
84907777/83995542 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/3753967; hsa-mir-10400/Downstream/7209943;
Nearest TSS
ENST00000518652/Upstream/82727; ENST00000522647/Downstream/187245;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2153199, chr8-CpG: 49/Downstream/188982
Upstream sequence
aggttttggagaacaagtggtatttggttacatgagtaagttctttagtggtgatttgtgagattttggtgcacccaccacccaagcagtatacatggaa
Downstream sequence
agtgggagagaagaataggtggatagtgttcaataggtacagtttccatgtatggaggtggaagtgttgcaaatgggtaggtgatggttgaacaacaatg
Target sequence
ccactcacaaaaggacaaatattatatgattctacttaaatgaggtatttagagaagtcaaactcatagagataaaaagttgaatggtagttgccaggagtt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate