Basic Information
VIS ID
TVIS10017292
Fusion event
HBV-LINC00710 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
647
End
737
Integrated sequence
GTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTT
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
10992138/10950175 (Hg38)
End
10992236/10950273 (Hg38)
Location type
Intron
Target gene
LINC00710
Nearest miRNA
hsa-mir-3155a/Upstream/4797898; hsa-mir-107/Downstream/1180487;
Nearest TSS
ENST00000439456/Upstream/151551; ENST00000420825/Downstream/9878;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/683549, chr10-CpG: 158/Downstream/67206
Upstream sequence
ttagggtcggggtcggggtcggggtcggggtcagggtcagggtcagggtgagggtgagggtgagggtgagggtcagggtgagggtgagggtgagggtgag
Downstream sequence
TGTGTGTCTGAGGACGGGAGGTGCAGGTGAGAGAATGGCCACTCTCATGTGCTTCTCTCTGTGGTCCCAGCGAGGTCTGGGTCTGAACAAATGGGGCAAA
Target sequence
GTTTGCACTGGGAAAGGGCCAGGGCCTGAACCGTGGTTTCTGAATCTTGGAGTTGCTAGAACCCCAGAGGTCATTACTAAGAAGAACCCAGTGCAGTG
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate