Basic Information
VIS ID
TVIS10017294
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1639
End
1730
Integrated sequence
TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
104255564/103603214 (Hg38)
End
104255659/103603309 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/1557210; hsa-mir-1267/Downstream/3927862;
Nearest TSS
ENST00000623511/Upstream/178014; ENST00000640578/Downstream/1862558;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/756801, chr13-CpG: 29/Downstream/2889751
Upstream sequence
GTATTGTGTATAAAATATAATTTTTTCTATGAGTCTtgtatgtgtgcatgtatttatgtatgtacatgtctgcatgtatgtatgtatctatCATATAGCT
Downstream sequence
atgaaacacaatttagtggttccttaaaaattaaacatagaattggtgtatgacctagccattccttgtctcctataacccgctaaattgaaagctgact
Target sequence
cctcataccaattagtatagctgatattggtaaggatgtggagacactggatcccttgtgaactgttggtgggaatgaaaaatagtgcagccact
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate