Basic Information
VIS ID
TVIS10017295
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1825
End
1917
Integrated sequence
TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
104255463/103603113 (Hg38)
End
104255568/103603218 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/1557109; hsa-mir-1267/Downstream/3927953;
Nearest TSS
ENST00000623511/Upstream/177913; ENST00000640578/Downstream/1862649;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/756700, chr13-CpG: 29/Downstream/2889842
Upstream sequence
GCTCAGTTAAttcctcaaagaagatatgtaaattgctaacaagcatatgaaaagatgctcgacattaccagtcattaggcaaatgcaaatcaaaccatta
Downstream sequence
ataccaattagtatagctgatattggtaaggatgtggagacactggatcccttgtgaactgttggtgggaatgaaaaatagtgcagccactatgaaacac
Target sequence
AGCTCAGTTAAttcctcaaagaagatatgtaaattgctaacaagcatatgaaaagatgctcgacattaccagtcattaggcaaatgcaaatcaaaccattacctc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate