FUT8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017296
Fusion event
HBV-FUT8 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
2296
End
2367
Integrated sequence
ATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCC
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
66018814/65552096 (Hg38)
End
66018894/65552176 (Hg38)
Location type
Intron
Fragile sites / regions
FRA14B
Target gene
FUT8
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-34a-5p ; hsa-mir-122-5p ; hsa-mir-26a-5p ; hsa-mir-455-3p
Nearest miRNA
hsa-mir-208a/Upstream/80910; hsa-mir-1185-1/Downstream/1889679;
Nearest TSS
ENST00000550708/Upstream/63778; ENST00000554765/Downstream/84340;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/138444, chr14-CpG: 40/Downstream/461439
Upstream sequence
gctactactgttgctctttatttgactaatagcatttctggagtaattctttccaggttttattccctgttgtgtgtaccggttaaaagatactgctcag
Downstream sequence
ATTCAGTTTCTGTTGAGTCACTCAGAATGTTAGTTGCTGTAAGAAGAGGCTTTTTTTCTTTTTTGGTTGTTTGTTTTAGTGGCATTACTTCACTTTGCAA
Target sequence
GTATGCAGGTGGCAGTGTTCAATTTTATGCTTAAAAATAAAATGATAGCAAAAAATGCAATTATTTGTGGAATAGTTTAT
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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