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VISDB
Viral Integration Site DataBase
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TVIS10017304
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017304
Fusion event
HBV-PDXK integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1058
End
1119
Integrated sequence
CCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTT
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
45148209/43728328 (Hg38)
End
45148278/43728397 (Hg38)
Location type
Intron
Target gene
PDXK
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-24-3p
;
hsa-mir-760
;
hsa-mir-744-5p
;
hsa-mir-484
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-mir-409-5p
;
hsa-mir-3187-3p
;
hsa-mir-4435
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-548s
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-3926
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-1252-5p
;
hsa-mir-214-3p
;
hsa-mir-221-5p
;
hsa-mir-3190-3p
;
hsa-mir-3202
;
hsa-mir-34a-5p
;
hsa-mir-34c-5p
;
hsa-mir-3619-5p
;
hsa-mir-4291
;
hsa-mir-4467
;
hsa-mir-449a
;
hsa-mir-449b-5p
;
hsa-mir-4533
;
hsa-mir-4690-5p
;
hsa-mir-548au-3p
;
hsa-mir-6087
;
hsa-mir-6124
;
hsa-mir-651-3p
;
hsa-mir-6868-5p
;
hsa-mir-761
;
hsa-mir-8073
;
hsa-mir-922
Nearest miRNA
hsa-let-7c/Upstream/118339; hsa-mir-6815/Downstream/1749869;
Nearest TSS
ENST00000624081/Upstream/6636;
ENST00000476313/Downstream/333;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/8378
,
chr21-CpG: 24/Downstream/176
Upstream sequence
TGTGGATCATAGGGCTGACCAGTGGCAGGCGGTGGGAGGGACGCGGGGTGCTTGTGCCCCAGGTTGATCAGGGTGAAGCAGTCACATGATCTCTCCTGTC
Downstream sequence
CTGGGTGGGTGGCTTCGGCTTCTGTGCAGCGCTCACCCTGCTCTCCCCTGGAACGCCTGGAACTAGGGTGGTCAGGCTGGGGTGGAGGAGCTCCCCTGGA
Target sequence
CTCTTTCCTCATTCTGGTTTCCTAAAGTGGTCAGAGGTCTCTGCAAAATAAGCTAAAGGGAGGGTTCTG
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Sample Information
×
Sample name
F11
Sample type
Tumor
Gender
Female
CpG Island Information
×
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