Basic Information
VIS ID
TVIS10017305
Fusion event
HBV-chr5 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
3124
End
3188
Integrated sequence
GCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
10478/10478 (Hg38)
End
10547/10547 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Downstream/1052349;
Nearest TSS
ENST00000502646/Downstream/81604;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/40143
Upstream sequence
GAGAATTTCATCCCACTCAATAGTGCATAATGACTGCGGGATAAATCAATGTCTTAGAAATCTGAAAAACTCTGAAAAAGAACATCTAATGTGACCTGCG
Downstream sequence
aaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacc
Target sequence
cctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccct
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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