ADCY1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017311
Fusion event
HBV-ADCY1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1712
End
1806
Integrated sequence
AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
45668032/45628433 (Hg38)
End
45668135/45628536 (Hg38)
Location type
Intron
Target gene
ADCY1
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-212-3p
Nearest miRNA
hsa-mir-1183/Upstream/746633; hsa-mir-10399/Downstream/11327249;
Nearest TSS
ENST00000635602/Upstream/53548; ENST00000646653/Downstream/20173;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/52528, chr7-CpG: 33/Downstream/98378
Upstream sequence
TATTAAATACGAGTTATGTGCTCAACTGTGAATttatatgaaaaggagattaggacacaacaggcatagaggaaagatcatgtgaagacacagggagaaa
Downstream sequence
CATGGGGAGTATATGAGGAGGCACCCCTGCCCTTCCCCAAGGCAGGACATCCCATGGGCTGTGTTTTGGTGTCTTTAGGAAAATTATTAAGAAGAGTTCT
Target sequence
TCACACAGCAGGGAAAGTGTTTCCCTGTCCTGGGATCCTTGCAGAGTGACCTGCCCAGACTCTATCAGGGGTGGAGGGTGAGCGGTTTCTGGAGGAAGGGGAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate