SNRPN _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017318
Fusion event
HBV-SNRPN integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
737
End
782
Integrated sequence
TATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTG
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
25075095/24829948 (Hg38)
End
25075151/24830004 (Hg38)
Location type
Intron
Target gene
SNRPN
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1268a/Upstream/1267817; hsa-mir-10393/Downstream/1018743;
Nearest TSS
ENST00000557528/Upstream/6223; ENST00000577949/Downstream/26547;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/56562, chr15-CpG: 30/Downstream/18040
Upstream sequence
aaacaatgatacaacttataattgaagacatcttagatttggtaaaatacTACAGACTTTGGTGTGTGATAATCATTCTCAAATTAGTCCTTTTAGATAG
Downstream sequence
ATTCTCTGAGGATATACACGTTTGTCAGTGTACGTGCATGACCGCTTACATGTTGATGTTCGCATACAAACCCCACAATTTTCTCATGTTTTTCAGAGCA
Target sequence
ACGGGCAAGGCAGGCAGGGGACTTCAGAGGTGGTAGCAGTGGGTGTTGATGAAATT
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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