Basic Information
VIS ID
TVIS10017320
Fusion event
HBV-chr19 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
236
End
326
Integrated sequence
AATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACC
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
59116312/58604945 (Hg38)
End
59116411/58605044 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/54569;
Nearest TSS
ENST00000633603/Upstream/5590;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/23039, None/Downstream
Nearby gene
RPL23AP79(-5461) ;
Upstream sequence
GCCGTCCGCCGCGGACAAGACCCTGGTGAGTCTACTGCCGCGGGCTGCGGACAGGGACTCCTGGGGCCCAGACCGCGCCGGGGAGCTGGGTgggggcggg
Downstream sequence
attttttatatattttgaatacaaattctcagatctgtattttgcaaatattttcttcaatatgtggcttgtctttttgttctcttaacaaggtctcttc
Target sequence
aagtgtacttgccatctgtagatcttctttggtgaggtgtctgttcagatctgtgtgcatttttaattgggctgtttaacttattgtttagttttaaca
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate