STK39 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017321
Fusion event
HBV-STK39 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1202
End
1293
Integrated sequence
ACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTG
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
168890582/168034072 (Hg38)
End
168890682/168034172 (Hg38)
Location type
Intron
Target gene
STK39
Nearest miRNA
hsa-mir-128-1/Upstream/7626190; hsa-mir-10b/Downstream/548771;
Nearest TSS
ENST00000437798/Upstream/21411; ENST00000392687/Downstream/78934;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/317748, chr2-CpG: 128/Downstream/212268
Upstream sequence
GTTTCTAAACACATGTAGATTCAAGCAAATAATAGCAATATGGACTTAGGTAAATCTTACTCTGCCAGATAGATCATACTTTAAGTGTGAAAGCATATTG
Downstream sequence
GCCCAGCATTGCTTGAGTAAACAGGCCCTGACCATGTGGAGGTGGAGACTGACACTCTGGCTTGGGGTTTGAAACAAAGAGACTGGGATTGACTTACCTT
Target sequence
GGTATCAAATCCTCCACTGAGTCCTACAGCAGCTGCTAACAATGAACCCAACATACATAACAAGATTTGGGGGAGGCAGGCCCCTGCATGTCCTCAAGCG
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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