TRIP12 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017327
Fusion event
HBV-TRIP12 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1731
End
1825
Integrated sequence
CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
230692544/229827828 (Hg38)
End
230692646/229827930 (Hg38)
Location type
Intron
Target gene
TRIP12
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-106b-5p ; hsa-mir-149-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10b/Upstream/2355641; hsa-mir-1244-1/Downstream/1534778;
Nearest TSS
ENST00000437798/Upstream/13335; ENST00000465090/Downstream/31352;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/112563, chr2-CpG: 150/Downstream/93266
Upstream sequence
ggggaggcctcaggacacttacaatcatggcggaaggtgaaggggaagcaaggcacgtcttacatggtggcaggagagagacagagagtgagcaaagaga
Downstream sequence
gactggactcccctggctctaaatgataaaagtatggtTTAAAAATCTGTACTGTATATTAGctagatgatgagcatttttcagctccattataatcttg
Target sequence
gctcaacagctatcattagtgttattatagttagggttaccgtattttatgtgtggcccaagacaattcttcttcttccaatgtggcccagggaagcaaaaa
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate