TRIP12 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017328
Fusion event
HBV-TRIP12 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2004
End
2092
Integrated sequence
TCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGA
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
230692661/229827945 (Hg38)
End
230692758/229828042 (Hg38)
Location type
Intron
Target gene
TRIP12
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-106b-5p ; hsa-mir-149-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10b/Upstream/2355758; hsa-mir-1244-1/Downstream/1534666;
Nearest TSS
ENST00000437798/Upstream/13452; ENST00000465090/Downstream/31240;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/112680, chr2-CpG: 150/Downstream/93154
Upstream sequence
ATCCTGTTGAGCTGCTCCATCTGCAGGGTGTAGCGGGCCTCCACCTCCCTCAGGCTGTTCTCCAAGCTGGCCTTCAGATTTCTCATGGAGTCCAGGTCCA
Downstream sequence
agtgtgtgtgaactgttgttgaatgaaacatcatcatgcagcacatgactgTatataatgcctgggattcatttcaaactaatatgggaagaaggattag
Target sequence
gctctaaatgataaaagtatggtTTAAAAATCTGTACTGTATATTAGctagatgatgagcatttttcagctccattataatcttgtgggactaatgt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate