Fusion event
HBV-SLC47A2 integration
Detection method
Capture-NGS platform
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
CATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATC
End
19595360/19692047 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/347404; hsa-mir-10226/Downstream/7601863;
Upstream sequence
ggccaggtgtagtgactcacgcctgtaatcccagcactttgggaggccaatgcgggaggattgcttgagtccaggaattcaagaccagcctgggcaacat
Downstream sequence
tgaaaccccgtctctaccacagatataaaaattagccagatgtggtggtgggcacctgtagtcccagctactcaggaggctgacgcaggagaatcgcttg
Target sequence
cagcactttgggaggcctaggtgggcagatcataaggtcaggaattcgagaccagcctggccaacatgg
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.