Basic Information
VIS ID
TVIS10017332
Fusion event
HBV-chr18 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2775
End
2852
Integrated sequence
ATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGG
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
1861366/1861365 (Hg38)
End
1861459/1861458 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-8078/Upstream/1749026; hsa-mir-1-2/Downstream/2023895;
Nearest TSS
ENST00000575820/Upstream/81036; ENST00000575515/Downstream/45188;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/951792, chr18-CpG: 33/Downstream/709829
Upstream sequence
caggtgatccacccacctcagcctcccaaagtgctgggattacagacatgagccaccatgcctggccTGttttttgttattttaaaagatagagtctcac
Downstream sequence
accatcacagcattccaagtcacaggatgaaataggaggtcagcacaagatgcaggtcacaaagaccttgctgataaaaggatgcagtaaagaagccagc
Target sequence
caaatattaatctcctttggaaacaccctcacagacacacccaggatcaatactttgtatccttcaatccaatcaagttgatgtttagtatta
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate