Basic Information
VIS ID
TVIS10017344
Fusion event
HBV-LOC107985342 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
2595
End
2680
Integrated sequence
AGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCAT
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54160010/53656756 (Hg38)
End
54160081/53656827 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LOC107985342
Nearest miRNA
hsa-let-7e/Upstream/1374863; hsa-mir-10394/Downstream/9852;
Nearest TSS
ENST00000633603/Upstream/24700; ENST00000597619/Downstream/105134;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7769, chr19-CpG: 23/Downstream/111659
Upstream sequence
ttgtcatttgttaaagagcttagcagttctaagagatatagaccagctgtgctatctttttgtggttttcagttctctagtatgttgagcatctttttgt
Downstream sequence
gtagagacagggttttgccgtgttgcccaggctgatctcgaactcctgacctcaggtgatcaccttccttggcctcccaaagtgttgggattacaggtgg
Target sequence
aaagcgctgggattacaggtgtgagccactgcacccagccaatttttgtattttttttttttttttttttt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate