Basic Information
VIS ID
TVIS10017354
Fusion event
HBV-LINC01934 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1069
End
1160
Integrated sequence
ATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGC
Host Sequence
Chromosome
chr2
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
182177901/181313174 (Hg38)
End
182177957/181313230 (Hg38)
Location type
Intron
Fragile sites / regions
FRA2G
Target gene
LINC01934
Nearest miRNA
hsa-mir-10b/Upstream/7522; hsa-mir-1244-1/Downstream/3065745;
Nearest TSS
ENST00000437798/Upstream/109818; ENST00000476089/Downstream/112519;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/331975, chr2-CpG: 119/Downstream/143804
Upstream sequence
TGAGCCCACTGCATGTCTGTGTCTCCAGATCCTCAGTGTCATGGAGCTGGACTCGTACCCTCTCTACGCCATCTACCTCATCGTCATTGGCCTCAGCGGT
Downstream sequence
ctttctttctttctctctctctctctctctctctctctttctttctttctttctttctttctttctttctttctttctttctttctttctctttctctct
Target sequence
AGGGTtttctttctttctttctttctttctttctttctttctttctttctttcttt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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