Basic Information
VIS ID
TVIS10017357
Fusion event
HBV-chr1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1424
End
1512
Integrated sequence
GTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCG
Host Sequence
Chromosome
chr1
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
121485152/121743354 (Hg38)
End
121485241/121743443 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/4648626; hsa-mir-1182/Downstream/24107144;
Nearest TSS
ENST00000473358/Upstream/162830; ENST00000443018/Downstream/21757069;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/223627, chr1-CpG: 312/Downstream/3342066
Upstream sequence
cctaaccctaaccctaacccaaccctaaccctaaccctaaccctaaccctaaccctaacccctaaccctaaccctaaccctaaccctaacctaaccctaa
Downstream sequence
tatagaaacaagacagaatgattctcagaaactcctttgtgatgtgtgcgttcaactcacagagtttaacctttcttttcatagagcagttaggaaacac
Target sequence
agagcagacttgaaacactctttttgtggaatttgcaagtggagatttcagccgctttgaggtcaatggtagaaaaggaaatatcttcg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate