hsa-mir-422a _LIHC.png
TERT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017366
Fusion event
HBV-TERT integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Start
2615
End
2704
Integrated sequence
AGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATT
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
End
1276418/1276303 (Hg38)
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-4635/Upstream/213231; hsa-mir-10397/Downstream/33007;
Nearest CpG islands
Nearest cancer related gene
TERT(OG, No orient, 0)
Upstream sequence
AATAAGGAGCtttgcaaatatggaaacttgagcaatgaatatttcagcaactgaccccactgtgagtaaatgggaggatcaagattcaaattctggtggg
Downstream sequence
CCACCTATCCCACACATGAAAACCAATCCCACAGATCCCCACCTACCCCACGGATGAAAACCAATTCACAGATCCCCACCTACCCCACGCATAAAAACCA
Target sequence
ATAGAAACCAATCCCACAGATCCCCACCTACCCCACGGATGAAAACCAATTCACAGATCTCCACCTACACCACACATGAAAACCAACTCCACAGATCC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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