Basic Information
VIS ID
TVIS10017369
Fusion event
HBV-chr9 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1360
End
1450
Integrated sequence
ATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCT
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
16393992/16393994 (Hg38)
End
16394087/16394089 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/10386090; hsa-let-7a-1/Downstream/2179217;
Nearest TSS
ENST00000422679/Upstream/117681; ENST00000430640/Downstream/42283;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/840658, chr9-CpG: 30/Downstream/332772
Upstream sequence
GCAGCCAGCCGGGCCTGGCGCAGCATCAGTGCCCGCTGCCGCTTCCGCTCGATACTCGCCCGCACCGAGGCAGGCAGCTCCGCGGGTTGCTCTAAAGCCG
Downstream sequence
tatcagttcccaaataatacttttataatttcttatgcctgtctttaatctcttaatcctgttatcttcataagctgaggatatatgtcacctcaggacc
Target sequence
TCAGTTGTGtgttgcgggaagtcagggaccccgaacggagggactggctggagctgtggcagaggaacatgaattgtgaagatttcatggacatt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate