Basic Information
VIS ID
TVIS10017375
Fusion event
HBV-chr12 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
938
End
1023
Integrated sequence
AAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGC
Host Sequence
Chromosome
chr12
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
34569759/34416824 (Hg38)
End
34569851/34416916 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/8542745; hsa-let-7i/Downstream/7906784;
Nearest TSS
ENST00000382841/Upstream/197971; ENST00000553138/Downstream/3899662;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/66145, chr12-CpG: 44/Downstream/3721310
Upstream sequence
agaagctcaaagctaaggtttctactcaatttcaataagaagtagcaattcagactttttgtcagttactgtacatttcctagcccctattacttgatta
Downstream sequence
ctcagtgcactcccaaatatcactttacagattctagaaaaacagtgttcccaaactgcttaatcaaaagaaaattttaactctgtgagatgaatgcaca
Target sequence
actctgttagataaatgcacacatcagaaagcagtctctcagaaatcttatttcaagtgtttatctacagatatttcctttttaccacagac
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate