PSKH2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017381
Fusion event
HBV-PSKH2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1371
End
1462
Integrated sequence
TTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCT
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
87092485/86080256 (Hg38)
End
87092581/86080352 (Hg38)
Location type
Intron
Target gene
PSKH2
Nearest miRNA
hsa-mir-12123/Upstream/5838783; hsa-mir-10400/Downstream/5125133;
Nearest TSS
ENST00000518652/Upstream/6367; ENST00000285393/Downstream/4500;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/10439, chr8-CpG: 100/Downstream/261963
Upstream sequence
GCTCTGCAGGCAGTGTGCGGCGCCAGGGCCCCACCGTCTCCTCCTGGACGTGGACCTCCAAGGCAGCCCTGAGCGCCCGGTCCAGCTCCTCCACATCCTG
Downstream sequence
aatatccatgtaaaaaaaatagagtgatgggaaagactaggaaaaccactgaagagggttgagagaaagtgtctcagagtgctatgcaggtcatcgggga
Target sequence
TGAGGGAAGAAGCTACCAAAGAGATACtgttattctagatcttccaagaagcagatgccaagacagaactaaatgtgcaaggattttattaggtgt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate