Basic Information
VIS ID
TVIS10017388
Fusion event
HBV-LOC112267879 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1824
End
1915
Integrated sequence
TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
67302718/67252294 (Hg38)
End
67302818/67252394 (Hg38)
Location type
Intronic
Target gene
LOC112267879
Nearest miRNA
hsa-let-7g/Upstream/26767; hsa-mir-12124/Downstream/1796564;
Nearest TSS
ENST00000440867/Upstream/253369; ENST00000498247/Downstream/43906;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/253445, chr3-CpG: 45/Downstream/401810
Upstream sequence
cgtgaggcatgctcctgcctcaggctctctgcctgccgtgctctcacctcgcagacccacgtgatttcctcccgaacccccttcaggcctcggtccaaac
Downstream sequence
tttcttttggatggagtcttgctctgttgcccaggctggagtgcagtggtgtgatctccactcactgcaagctctgctgcctcccggagtcatgccattc
Target sequence
aggggatctggtgggaggtgattggatcattgaggtggtttcccccatattggtctcatgatagtgagttctcatgagatctgatgtttttgtttttctt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate