Basic Information
VIS ID
TVIS10017392
Fusion event
HBV-chr9 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1093
End
1178
Integrated sequence
CACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCC
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh37/hg19
Start
12085884/12085884 (Hg38)
End
12085978/12085978 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/6077980; hsa-let-7a-1/Downstream/6487328;
Nearest TSS
ENST00000422679/Upstream/809570; ENST00000473763/Downstream/73169;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/467296, chr9-CpG: 28/Downstream/689509
Upstream sequence
ATGGCTTTCTCTCTCCTGATAAACTGTCTTTGCTGGAAAAACTCCTACCCGAGAGGAAGGAAGTGGAAGAGACTGATGAGATGGACCAAGTAGAACTGGT
Downstream sequence
taaaacttatattaaataattctgtGCCATCTTAATCCTAGAaatgcatgatctttttcacagactggtttattttctttcggatatatacccagtaatg
Target sequence
aactatttttttacccaattttatatgtaagtacttgactcaaactgctttttttttttaaatcttcatttcctattaggtcttttgtgtcatt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate