BBS7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017402
Fusion event
HBV-BBS7 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
3139
End
3188
Integrated sequence
GTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr4
Cytoband
q27
Reference genome
GRCh37/hg19
Start
122757725/121836570 (Hg38)
End
122757774/121836619 (Hg38)
Location type
Intron
Target gene
BBS7
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12113/Upstream/7179716; hsa-mir-1305/Downstream/3670640;
Nearest TSS
ENST00000502981/Upstream/7897; ENST00000567769/Downstream/22404;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/12458, chr4-CpG: 50/Downstream/33426
Upstream sequence
CATCTGTCATGTCTTTGTGTTCAGGGTAAAAAACTTGTTGCTGCAAGTCAAGCTGCCTTAGGCTTATAACATCACATTTAAAAGCATCTCAGGTAACtat
Downstream sequence
agttctacttttctgcttctacaagcaatgctgcaattaattatattcatgtctgttatgtatattactgctattttattgccattaatagattccccca
Target sequence
ataaatagctatttattcaacccttcaatcattaatgagtattcacctt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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