Basic Information
VIS ID
TVIS10017404
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
3111
End
3188
Integrated sequence
GCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
84038710/83464575 (Hg38)
End
84038795/83464660 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/5766459; hsa-mir-1267/Downstream/4154005;
Nearest TSS
ENST00000623511/Upstream/2214137; ENST00000446314/Downstream/417733;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2809265, chr13-CpG: 18/Downstream/414869
Upstream sequence
ctgactataaggtgagtttatcattttttcttaaacaattatcacttagagaagagggactttgatattacatggtatgggctttattattaatacttaa
Downstream sequence
cactaaaaaaccacacaattacatggaaattgagcaacctgctccagaacggctcctgaggaaataaggaaattaaggcaggaatcaagaagttctctga
Target sequence
tctgcaaatgcaaaagaactgaaatcataacaaacagtctctcagaccacagtgcaatcaaattagaactcaagatttaaaaacc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate