Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017414
Fusion event
HBV-ZMAT4 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
485
End
575
Integrated sequence
TCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACC
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
Start
End
40722836/40865317 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-7977 ; hsa-mir-6131 ; hsa-mir-1207-3p ; hsa-mir-6768-5p ; hsa-mir-2909 ; hsa-mir-1296-5p ; hsa-mir-383-3p ; hsa-mir-4761-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-8485 ; hsa-mir-4436b-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-335-3p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-7107-3p ; hsa-mir-6753-3p ; hsa-mir-6503-5p ; hsa-mir-4527 ; hsa-mir-9-5p ; hsa-mir-302a-5p ; hsa-mir-3121-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-501-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p
Nearest miRNA
hsa-mir-124-1/Upstream/10907918; hsa-mir-10400/Downstream/405731;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1342252, chr8-CpG: 20/Downstream/32328
Upstream sequence
agaaaattagacctagatctaatgtcactctggtctcacttaacaaagcttaaaagcaagacataaaaggatcaaactgtttccaatgaacttaactgca
Downstream sequence
ATCCCTCTGAAAATGTCACCTTCCAGAAAAAAGAAATCTTCCCCGAATTCGGCCTGCATCACCACTGCAGCCTGTGCTAGGCCGTGCAGATCTGGGCCAT
Target sequence
AAGGAAGACATGAAAGCAAAATACAAGGTGCAAATACAAGCCACGACTGAT
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.