PRDM7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017427
Fusion event
HBV-PRDM7 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1703
End
1818
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
90139803/90073395 (Hg38)
End
90139863/90073455 (Hg38)
Location type
Intron
Target gene
PRDM7
Nearest miRNA
hsa-mir-11401/Upstream/1357058;
Nearest TSS
ENST00000527434/Upstream/11070; ENST00000563357/Downstream/2470;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/20282, chr16-CpG: 31/Downstream/3820
Upstream sequence
tcgagtccactcgatgattccattcgagtccatttaatgaatccattggtttcaattctatgatgattacattggattccattcgttgatgaattcattc
Downstream sequence
gtggtgctatctcagctcactgcaagctccgcctcccgggttcatgccattctcctgcctcagcctcctgagtagctgggactacaggtgcccgccaccg
Target sequence
ATGACAAtttttttttttttttgagatggagtctcgctctgtcgcccaggccggagtgca
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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