Basic Information
VIS ID
TVIS10017428
Fusion event
HBV-LINC00607 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
673
End
786
Integrated sequence
TCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTC
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216499657/215634934 (Hg38)
End
216499779/215635056 (Hg38)
Location type
Intron
Target gene
LINC00607
Nearest miRNA
hsa-mir-10b/Upstream/1876775; hsa-mir-1244-1/Downstream/2265457;
Nearest TSS
ENST00000437798/Upstream/13581; ENST00000428487/Downstream/42968;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/198797, chr2-CpG: 51/Downstream/378120
Upstream sequence
CCAGCCAGGGCAGAGGTTCCCTAGGCAACGAGGGAGAGAGGGAGGGGCCTCCAGAAGGGAGAGAGAGAAACCGGTTGCCCCAGGTTCGGTGAAGTCTGGG
Downstream sequence
gttgcacctgcctgcagagttcaagtagaagcaggactgctggactaaaagctctggtgggtgtgggcagtctggctatgagagacaggagtcagtgaag
Target sequence
cttttgttgggtgttctggtccatggggctccctcaggcaggggtcacaattgacagacaggttgtatccttgccaggctggccctaatttgtgtctgagtgcctcctgcgggaaatgtgag
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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