VISDB Viral Integration Site DataBase

VIS ID

TVIS10017433

Fusion event

AAV2-CCNA2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2018

PubMed ID

Virus name

AAV2

Reference genome

Start

4316

End

4597

Integrated sequence

CAAGTCTGTTAATGTGGACTTTACTGTGGACACTAATGGCGTGTATTCAGAGCCTCGCCCCATTGGCACCAGATACCTGACTCGTAATCTGTAATTGCTTGTTAATCAATAAACCGTTTAATTCGTTTCAGTTGAACTTTGGTCTCTGCGTATTTCTTTCTTATCTAGTTTCCATGGCTACGTAGATAAGTAGCATGGCGGGTTAATCATTAACTACAAGGAACCCCTAGTGATGGAGTTGGCCACTCCCTCTCT

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

122743844/121822689 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-146a-5p ; hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-98-5p ; hsa-mir-197-3p ; hsa-mir-10b-3p ; hsa-mir-130b-3p ; hsa-mir-27b-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-4676-5p ; hsa-mir-575 ; hsa-mir-548e-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6835-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-22-3p

Nearest miRNA

hsa-mir-12113/Upstream/7165826; hsa-mir-1305/Downstream/3684570;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/21077, chr4-CpG: 71/Downstream/713

Upstream sequence

TAAAGATCTAAGTAAAGTAGGTTTGAACTGTTATTGGTTATTTAAGTTTATtacatacacatacatgcatagatatatatatatatatTATGTTTTTATG

Downstream sequence

ATTCTTTCTCTTATGGGTGTTGGCCTTTGCTTTTTCTCCCAAATACTCTATCAGGAATTAAACTTTCTGGGACAAAGAAGAGTTTCAGTATTCAAAAGAG

Target sequence

TAGTCTTGC