Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017434
Fusion event
AAV2-CCNA2 integration
Validated
No
Detection method
WES
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
AAV2
Reference genome
Start
4613
Integrated sequence
GCGGGTTAATCATTAACTACAAGGAACCCCTAGTGATGGAGTTGGCCACTCCCTCTCTGCGCGCTCGCTCGCTCACTGAGGCCGGGCGACCAAAGGTCGC| |CCGACGCCCGGGCTTTGCCCGGGCGGCCTCAGTGAGCGAGCGAGCGCGCAGAGAGGGAGTGGCCAA
Host Sequence
Chromosome
chr4
Cytoband
q27
Reference genome
End
122743570/121822415 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-146a-5p ; hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-98-5p ; hsa-mir-197-3p ; hsa-mir-10b-3p ; hsa-mir-130b-3p ; hsa-mir-27b-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-4676-5p ; hsa-mir-575 ; hsa-mir-548e-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6835-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-22-3p
Nearest miRNA
hsa-mir-12113/Upstream/7165561; hsa-mir-1305/Downstream/3684844;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/20812, chr4-CpG: 71/Downstream/987
Upstream sequence
CTTGAAGATTTACCACGGGAAGGGAATTCAGCTATCCCAGGGTGATGAGAACTGGATTCCTTTGTATTTGTGAAGATGCCAGATTCTGAGCCCCTAGACT
Downstream sequence
CATTGGATAATCAAGAGGGACCAATGGTTTTCTGGGTCCAGGTAAACTAATGGCTGAATTAAAAGCCAGGGCATCTTCACGCTCTATTTTTTGAGATTCA
Reference
Bayard, Q., et al. Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress. Nat Commun ,2018,9(1): 5235.