VISDB Viral Integration Site DataBase

VIS ID

TVIS10017436

Fusion event

AAV2-CCNA2 integration

Validated

No

Detection method

WES

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2018

PubMed ID

Virus name

AAV2

Reference genome

Start

4064

End

4586

Integrated sequence

TCCACACACGGACGGACATTTTCACCCCTCTCCCCTCATGGGTGGATTCGGACTTAAACACCCTCCTCCACAGATTCTCATCAAGAACACCCCGGTACCTGCGAATCCTTCGACCACCTTCAGTGCGGCAAAGTTTGCTTCCTTCATCACACAGTACTCCACGGGACAGGTCAGCGTGGAGATCGAGTGGGAGCTGCAGAAGGAAAACAGCAAACGCTGGAATCCCGAAATTCAGTACACTTCCAACTACAACAA

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

122743742/121822601 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-146a-5p ; hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-98-5p ; hsa-mir-197-3p ; hsa-mir-10b-3p ; hsa-mir-130b-3p ; hsa-mir-27b-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-4676-5p ; hsa-mir-575 ; hsa-mir-548e-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6835-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-22-3p

Nearest miRNA

hsa-mir-12113/Upstream/7165733; hsa-mir-1305/Downstream/3684658;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/20984, chr4-CpG: 71/Downstream/801

Upstream sequence

CTCAAGAAACCTAGGAAAAGTGGGCAGCAAATGTTGTAAACATCCTGAAGCAAAAAGAATGCCCTGTGCAGAAGACTATGTGAGTCtttaaaaaaatata

Downstream sequence

TTCCAAGGAGGAACGGTGACATGCTCATCATTTACAGGAAGATCCTTAAGGGGTGCAACCTAAAAAAAAATTAATAACTGGCTTTGAGCCTACTAGTCTT

Target sequence

TTCCAAGGAGGAAC