VISDB Viral Integration Site DataBase

VIS ID

TVIS10017437

Fusion event

AAV2-CCNE1 integration

Validated

No

Detection method

WES

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

AAV2

Reference genome

Start

4239

Integrated sequence

TCTCATCAAGAACACCCCGGTACCTGCGAATCCTTCGACCACCTTCAGTGCGGCAAAGTTTGCTTCCTTCATCACACAGTACTCCACGGGACAGGTCAGC| |GTGGAGATCGAGTGGGAGCTGCAGAAGGAAAACAGCAAACGCTGGAATCCCGAAATTCAGTACACTTCCAACTACAACAAGTCTGTTAATGTGGACTTTA

Chromosome

chr19

Cytoband

q12

Reference genome

Start

End

30291515/29800608 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-15b-5p ; hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-185-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-16-1-3p ; hsa-mir-195-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-342-5p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-383-3p ; hsa-mir-497-5p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-7-5p ; hsa-mir-4477a ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5191 ; hsa-mir-646 ; hsa-mir-25-5p ; hsa-mir-30c-2-3p ; hsa-mir-144-5p ; hsa-mir-892b

Nearest miRNA

hsa-mir-10395/Upstream/9401254; hsa-let-7e/Downstream/5322092;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/75921, chr19-CpG: 137/Downstream/10780

Nearest cancer related gene

CCNE1(OG, No orient, 0)

Upstream sequence

agtggatattcagacctctttgaggccttcgttggaaacgggatttctttatattatgctagacagaagaattctcagtaacttccttgtgttgtgtgta

Downstream sequence

ttgacaccagcctgggcaacatagtgagaccctgtctctacaaaaaaaaaagaaaaaaaatccaaaattggccaggtgcagtggctcacgcctgtaatcc