VISDB Viral Integration Site DataBase

VIS ID

TVIS10017443

Fusion event

HBV-CCNE1 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

885

Integrated sequence

GTGGGCCCTCTCACTGTAAATGAAAAGAGAAGATTGAAATTAATTATGCCTGCTAGATTCTATCCTACCCACACTAAATATTTGCCCTTAGACAAAGGAA| |TTAAACCTTATTATCCAGATCAGGTAGTTAATCATTACTTCCAAACCAGACATTATTTACATACTCTTTGGAAGGCTGGTATTCTATATAAGCGGGAAAC

Chromosome

chr19

Cytoband

q12

Reference genome

Start

End

30300450/29809543 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-15b-5p ; hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-185-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-16-1-3p ; hsa-mir-195-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-342-5p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-383-3p ; hsa-mir-497-5p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-7-5p ; hsa-mir-4477a ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5191 ; hsa-mir-646 ; hsa-mir-25-5p ; hsa-mir-30c-2-3p ; hsa-mir-144-5p ; hsa-mir-892b

Nearest miRNA

hsa-mir-10395/Upstream/9410189; hsa-let-7e/Downstream/5313157;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/84856, chr19-CpG: 137/Downstream/1845

Nearest cancer related gene

CCNE1(OG, No orient, 0)

Upstream sequence

ggtgttctcaaaaaaagggagtggcagggtgtggtagcacccgcccataactctaacactttgggagactaaggtgggaggatcgcttgaggccaggagt

Downstream sequence

aaagtgcacaaatcctaggtgtgaacttttatgtatgtatcaatcaatgagcttttatgtatgtatacagtcatgaaaccaccactcagatcaaagcata