Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017450
Fusion event
HBV-C8B integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
Polymerase;
Start
1274
Integrated sequence
GCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGC| |GGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCA
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
Start
End
57399017/56933344 (Hg38)
Location type
Exonic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/1707621; hsa-mir-101-1/Downstream/2799883;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/287780, chr1-CpG: 222/Downstream/488947
Upstream sequence
acttccttctctgctgcaacctggtgtctcatcgtgttaacttgctgtgtgcaccaggcaacagacctattacagtTCCAGTGTAGGGAGCACACTACCT
Downstream sequence
tgtgggagggacccagggggagattattgaatcacgggggtggtttcccccatactgttctcatggtagtgaataagtctcacaaggtctgatggtttta
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.