VISDB Viral Integration Site DataBase

VIS ID

TVIS10017451

Fusion event

HBV-PEA15 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

748

Integrated sequence

GGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATG| |TGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTACTAAAAC

Chromosome

chr1

Cytoband

q23.2

Reference genome

Start

End

160177041/160207251 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-212-3p ; hsa-mir-34a-5p ; hsa-mir-124-3p ; hsa-mir-122-5p ; hsa-mir-877-3p ; hsa-mir-155-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-3667-3p ; hsa-mir-493-3p ; hsa-mir-5009-3p ; hsa-mir-1224-3p ; hsa-mir-1306-5p ; hsa-mir-3651 ; hsa-mir-6769a-3p ; hsa-mir-3943 ; hsa-mir-4323 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1184 ; hsa-mir-1205 ; hsa-mir-1229-5p ; hsa-mir-17-3p ; hsa-mir-197-5p ; hsa-mir-3132 ; hsa-mir-3157-3p ; hsa-mir-3158-5p ; hsa-mir-3184-5p ; hsa-mir-346 ; hsa-mir-3677-5p ; hsa-mir-377-5p ; hsa-mir-3940-5p ; hsa-mir-423-5p ; hsa-mir-4288 ; hsa-mir-4435 ; hsa-mir-4507 ; hsa-mir-4519 ; hsa-mir-4688 ; hsa-mir-486-3p ; hsa-mir-541-3p ; hsa-mir-5693 ; hsa-mir-632 ; hsa-mir-654-5p ; hsa-mir-656-5p ; hsa-mir-6721-5p ; hsa-mir-6743-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6793-5p ; hsa-mir-6886-3p ; hsa-mir-874-3p ; hsa-mir-92a-2-5p ; hsa-mir-938

Nearest miRNA

hsa-mir-101-1/Upstream/307172; hsa-mir-1182/Downstream/1019935;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/1339, chr1-CpG: 53/Downstream/54714

Nearest cancer related gene

PEA15(TSG, No orient, 0)

Upstream sequence

GGGTGGCGAGGGTCGCACCAGGACCCTGGGCTTAACATGGCTTTTGCTCACTTTTGCCCAGCTTCCACCATTTCTTTCTGGGGGCAGGGGGTGGGGGGAC

Downstream sequence

gatcgcaccattgcactccagcctgggtgagagtgagactccgtctAAaataatgatgataataataataataataGGACACATATTTTCTTTGAATTTT