VISDB Viral Integration Site DataBase

VIS ID

TVIS10017453

Fusion event

HBV-LARP4B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1796

Integrated sequence

TGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTG| |GTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG

Chromosome

chr10

Cytoband

p15.3

Reference genome

Start

End

906376/860436 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-30a-5p ; hsa-let-7d-5p ; hsa-mir-218-5p ; hsa-mir-4642 ; hsa-mir-542-3p ; hsa-mir-4504 ; hsa-mir-3622b-5p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4715-5p ; hsa-mir-106a-3p ; hsa-mir-191-3p ; hsa-mir-603 ; hsa-mir-6776-3p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-6822-3p ; hsa-mir-21-3p ; hsa-mir-3591-3p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6873-3p

Nearest miRNA

hsa-mir-5699/Upstream/218658; hsa-mir-107/Downstream/1215583;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/50491, chr10-CpG: 134/Downstream/70913

Upstream sequence

ttgaatgcacacaacacaaagaagtgactgggaattcttctgtctagcattataggaggaaatcccgtttccaacgaaggcctcaaagaggtcctaatat

Downstream sequence

gcctgtagtcccatcttagggaggctgaggcaggagtatcacctgagcccaggagttcaaggctgcagtgagctatgattacaccactgcactttaggtg