Basic Information
VIS ID
TVIS10017459
Fusion event
HBV-chr11 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;Polymerase;
Start
1614
Integrated sequence
GACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGA| |CCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGA
Host Sequence
Chromosome
chr11
Cytoband
q25
Reference genome
GRCh37/hg19
Start
134282027/134412133 (Hg38)
End
134282027/134412133 (Hg38)
Location type
upstream
Nearest miRNA
hsa-let-7a-2/Upstream/513552;
Nearest TSS
ENST00000527297/Upstream/215; ENST00000532652/Downstream/151263;
Nearest CpG islands
chr11-CpG: 149/Target, None/Upstream, None/Downstream
Nearby gene
B3GAT1(+) ;
Upstream sequence
cctaaccctaaacctaaccctaccctaaccctaaccctaaccctactcctaaccctaacccctaacccctaatcctaacccaaaccctaaccctaaccca
Downstream sequence
cattgtaaataaagttttattgggcattcatgcctatttattgacatattgtctgtggctgctttagcactgtgatgacagagctcagtggttagaagta
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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