Fusion event
HBV-A2M integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein;Polymerase;
Integrated sequence
TGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACC| |GTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTT
End
9229442/9076846 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-141/Upstream/2112655; hsa-let-7i/Downstream/162621;
Upstream sequence
cgaggccgaccgaggccgaccgaggccgaccgaggccatccgaggccgaccgaggccgaccgaggccgaccgaggccgaccgaggccatccgaggccgac
Downstream sequence
GGGAGCGATCAGGTCCAGTTTGAGCTCAACTGCTACTCGCTGGCTCCCCAGATAAAGGTCATTGCTCCCTGGAGCATGCCTGAGTTCTACAACCGGTTCA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.