GTSF1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017461
Fusion event
HBV-GTSF1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
core protein;X protein;
Start
1818
Integrated sequence
GTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
End
54850350/54456566 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/119252; hsa-let-7i/Downstream/2737938;
Upstream sequence
ctcctgagtagctgggattgcaggcattcatcaccacacccaggtaatttttttattatctgtatagacggggtcttgctatgttgcccaggctagtctc
Downstream sequence
gatttcttaatataaaactagacacaagaattctcagaaacttctttgtgatgtgtgtattcaactcacagaggtgaaccttccttttgatagagcagtt
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate