VISDB Viral Integration Site DataBase

VIS ID

TVIS10017463

Fusion event

HBV-FNDC3A integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1825

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAAT

Chromosome

chr13

Cytoband

q14.2

Reference genome

Start

End

49761424/49187288 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-1-3p ; hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-573 ; hsa-mir-646 ; hsa-mir-3616-5p ; hsa-mir-4635 ; hsa-mir-4670-3p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-142-3p ; hsa-mir-206 ; hsa-mir-561-3p ; hsa-mir-551b-5p ; hsa-mir-613 ; hsa-mir-1303 ; hsa-mir-544a ; hsa-mir-7850-5p ; hsa-mir-6505-5p ; hsa-mir-202-3p ; hsa-mir-323a-3p ; hsa-mir-4668-3p ; hsa-mir-302c-5p ; hsa-mir-513a-5p ; hsa-mir-3143 ; hsa-mir-3160-5p ; hsa-mir-4711-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-499b-5p ; hsa-mir-4494 ; hsa-mir-543 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-129-5p

Nearest miRNA

hsa-mir-2276/Upstream/4991088; hsa-mir-1267/Downstream/809127;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/210382, chr13-CpG: 150/Downstream/32962

Upstream sequence

ACTGTCATCGCCCCGGGGTGGGGAGGACGGTGGGGCCCGTGTGGTTCGCAATGCCCCACATCCTGCACCTCAGGGGTCTGAGGACAGCTGCTCCCCGGCT

Downstream sequence

CATGATTTCAAACCGGAAAGAAAATTACACAGCAATAAAATATAGCGGCATGAGAACTTACATTTGTCTTCAGGGTCCACACATGAGATACATTTGTTAT