Fusion event
HBV-TNFAIP2 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CAACGGTCAGGTCTTTGCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTC| |TGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAA
End
103601621/103135284 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1185-1/Upstream/595558; hsa-mir-12121/Downstream/982121;
Upstream sequence
TAATACATAAGGATTTTGAAGATTGCAACAATAAATTACCATGTTTTATTCTGACACTGTACATATATTTTGATTTTCAAATTATAGTATTATAACTGTG
Downstream sequence
CCGGAGCATCTTGGACGTCAGCATGGGGGCGCAGGAGCCCTCCCGGCCCCTATTTTCCCTTATAAAGGTTGGTTAGCTTTTCCTGTGGCCTGACCTGCCT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.