Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017465
Fusion event
HBV-GANC integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
458
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
Start
End
42618538/42326340 (Hg38)
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-1233-1/Upstream/126674; hsa-mir-10393/Downstream/1467319;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/52134, chr15-CpG: 25/Downstream/164421
Upstream sequence
ACCTGATGAAAGATACACCACAGGGTGAGAGCATCCTAACAGCAAACTGCAAATGAGGTGGGTTTGCAGCTGCACAGAGAAGGGACCCCAGGGAAGCTAC
Downstream sequence
ACTCAGTATATGTGAAGGCCAAAGATCAGGGCTTCTTTGTGAAGAATCAGGAAGGGGAAGACTTTGAAGGGGTGTGTTGGCCAGGTATGAAATCACTTTA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.