Basic Information
VIS ID
TVIS10017467
Fusion event
HBV-chr15 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
Polymerase;
Start
1162
Integrated sequence
TATGCATGTATACAAGCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGAACCTTTACCCCGTTGCTCGGCAAC| |GGTCAGGTCTTTGCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCC
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
79165065/78872723 (Hg38)
End
79165065/78872723 (Hg38)
Location type
upstream
Nearest miRNA
hsa-mir-10393/Upstream/3110408; hsa-mir-11181/Downstream/337065;
Nearest TSS
ENST00000557528/Upstream/25056; ENST00000557961/Downstream/53;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/40515, chr15-CpG: 79/Downstream/202
Nearby gene
MORF4L1(+) ;
Upstream sequence
GTGAACATTTGTCTTACATAAAACTGATGAGACCTCCAAACCTTCATGTCCTGACAGCTTGTGGTCATCAGTGATCCCCACATCAAGATTGATCCTGACT
Downstream sequence
cctcccccacccggggggggggggggggcgccTCCACCGACTCCGAACTACCAGTCCCGGCGTGCCCTggggcggcgcgggcgcaggggcgcgtgcgcgg
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate