Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017475
Fusion event
HBV-CCDC85A integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;Polymerase;
Start
1527
Integrated sequence
CGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGC| |ACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGC
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
Start
End
56559841/56332706 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1301/Upstream/331911; hsa-mir-10b/Downstream/4054656;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/147302, chr2-CpG: 81/Downstream/1713801
Upstream sequence
cgtagcttcaccccattggctcctcaaccaagcacatgtctgaacttgccattcctctcatgctgagcaggattaccattgcaacaacacacatcacgga
Downstream sequence
ctccctGCTCTACCTTTTTGAGCCTGGTGAACACTTAAGACTTTTTATTGAAATTACCCACCACTGGTTGAATCTGACATCATTTGAGAACCTGTCCAAA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.