Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAA
End
216280280/215415557 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1657398; hsa-mir-1244-1/Downstream/2484956;
Upstream sequence
tctaaatcaagcttgttcaatgcatggcccaggatggctttgaatgcagcccaacaaaaattcgtaaagtttcttaaaatattgtaagatttttttttaa
Downstream sequence
AGTTTTATTTTTATTCAAGAAGTTTACTCCCAAATCACACCATTGATCCATCAAATTATTAAGTGATTAAATTTATTTTTTTTCCAAAATCAGTTGTCAA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.