VISDB Viral Integration Site DataBase

VIS ID

TVIS10017479

Fusion event

HBV-DDX17 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1804

Integrated sequence

ACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

38879564/38483559 (Hg38)

Location type

3UTR

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-744-5p ; hsa-mir-18a-3p ; hsa-mir-331-3p ; hsa-mir-106b-5p ; hsa-mir-27b-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-378c ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-432-3p ; hsa-mir-377-3p ; hsa-mir-218-5p ; hsa-mir-539-3p ; hsa-mir-6883-3p ; hsa-mir-3606-5p ; hsa-mir-3613-5p ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-1266-3p ; hsa-mir-454-5p ; hsa-mir-190a-3p ; hsa-mir-5690

Nearest miRNA

hsa-mir-1286/Upstream/494706; hsa-let-7a-3/Downstream/2330324;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/15301, chr22-CpG: 145/Downstream/21989

Upstream sequence

TTATACCTACAAAAAGAAAACAAGATGATGGTATCAAAAGGACAATTTACAAACTAAGAATAGTAACATAGCTTTCAGCATCCTGTGCCTGAACATCACA

Downstream sequence

CATCTACAAGTCTTTCAAGTCTTAATGCAACAGGAATGTGTCTGGAGACCAGCAAGAACATCAATAGAGAGCACTGATCCCAAGCAAAAGCCACTAACCT