MASP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017484
Fusion event
HBV-MASP1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1789
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCA| |TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr3
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
186966561/187248773 (Hg38)
End
186966561/187248773 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
MASP1
miRNAs that regulate target gene
hsa-mir-125a-5p
Nearest miRNA
hsa-let-7g/Upstream/461996; hsa-mir-28/Downstream/1440008;
Nearest TSS
ENST00000440867/Upstream/3797; ENST00000636210/Downstream/4428;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/48805, chr3-CpG: 25/Downstream/421353
Upstream sequence
CTCTGGCTTTCGTGTTTTTGGTTTTCTCCTTCCCAAGGCAGCTGGATTGAAAAAACAAAACAAAACAAAAAAACCCAGGGGCGTCAGTCGATATTCCCAG
Downstream sequence
AAAATGCCCCCTCCTTCCCCATGCTAGGCTCTGACTCCAGCTACATCATATGAAAAGGAAAAATTTCATCATATGAAAAGGAAAAGAACAATCGTATTTT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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