Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017485
Fusion event
HBV-C1QTNF7 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1735
Integrated sequence
TCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGA| |GGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCC
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
Start
End
15347266/15345642 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/1717685; hsa-mir-12115/Downstream/5182633;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/340505, chr4-CpG: 145/Downstream/309099
Upstream sequence
GTGACTACCCCATAATGGCATCCTGAAGCCTCATCCCCACACACCAAACATATTTTTGAAGGTCTTGAAGATCCAGTAGAAACACTTCGTAAAGTAGAGC
Downstream sequence
caacacataaattaatatttaaataaggtgttccgtcacTCAGCAAACAGGTGTTCAATAATCATCAGCAAAATAGGTGGCCAACAGATGATAAAACAGC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.