VISDB Viral Integration Site DataBase

VIS ID

TVIS10017492

Fusion event

HBV-PPP2CB integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

1373

Integrated sequence

CGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCC| |ATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGT

Chromosome

chr8

Cytoband

p12

Reference genome

Start

End

30643459/30785943 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-425-5p ; hsa-mir-421 ; hsa-mir-183-5p ; hsa-mir-218-5p ; hsa-mir-4753-3p ; hsa-mir-549a ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-6814-5p ; hsa-mir-130b-5p ; hsa-mir-216b-5p ; hsa-mir-548b-3p ; hsa-mir-150-5p

Nearest miRNA

hsa-mir-124-1/Upstream/828595; hsa-mir-10400/Downstream/10485105;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/57809, chr8-CpG: 41/Downstream/25991

Nearest cancer related gene

PPP2CB(TSG, No orient, 0)

Upstream sequence

agaaaattagacctagatctaatgtcactctggtctcacttaacaaagcttaaaagcaagacataaaaggatcaaactgtttccaatgaacttaactgca

Downstream sequence

CAGTTAGTTACCTTTTTTGCTTGAACAGTCCAAAGGAAAATGGTTACTATAAATACAGCAGGCAAACTGTTAGACTGACCTAGAACATAGTGTACTAAAT